Frequency of Her2/Neu Immuno Histochemical Expression in Bladder Urothelial Carcinoma: A Study At CMH Quetta

Introduction: The staining pattern of HER2/Neu expression in urothelial bladder cancer has been established for more than a decade, and literature review the past reveals dismal prognosis Her2/Neu expressed invasive carcinoma. Aims & Objectives: To determine frequency immuno histochemical carcinoma bladder. Place duration study: This descriptive, cross-sectional study was performed at Department Pathology, Combined Military Hospital, Quetta from 15th May 2017 to 14th November 2017. Material Methods: A total 89 patients with bladder, 20 60 years age, irrespective gender were included. Patients already histochemistry report taking radiotherapy excluded. processing done results interpreted (positive/negative) Her2/ Neu receptor. Results: participants this research ranged old an average age 44.16± 8.27 male female ratio 1.6:1.38. One every four (1.6:1) (42.70 percent) individuals studied cases found have over Conclusion: concluded that is very high.